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| First Round Draft Pick History |
| 1 | 4 | 4 | 2001 | Inaugural Draft | SS | Alex | Rodriguez | MLB |
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| 1 | 2 | 2 | 2000 | Annual Draft | OF | Albert | Belle | MLB |
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| Complete Draft History |
| 1 | 4 | 4 | 2001 | Inaugural Draft | SS | Alex | Rodriguez | MLB |
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| 2 | 4 | 12 | 2001 | Inaugural Draft | OF | Shawn | Green | MLB |
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| 3 | 4 | 20 | 2001 | Inaugural Draft | P | Roy | Oswalt | MLB |
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| 4 | 4 | 28 | 2001 | Inaugural Draft | P | Woody | Williams | MLB |
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| 5 | 4 | 36 | 2001 | Inaugural Draft | OF+ | Albert | Pujols | MLB |
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| 6 | 4 | 44 | 2001 | Inaugural Draft | 1B | J.T. | Snow | MLB |
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| 7 | 4 | 52 | 2001 | Inaugural Draft | 2B | Eric | Young | MLB |
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| 8 | 4 | 60 | 2001 | Inaugural Draft | 3B | Corey | Koskie | MLB |
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| 9 | 4 | 68 | 2001 | Inaugural Draft | P | Kevin | Jarvis | MLB |
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| 10 | 4 | 76 | 2001 | Inaugural Draft | OF | Juan | Pierre | MLB |
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| 11 | 4 | 84 | 2001 | Inaugural Draft | SS+ | Edgar | Renteria | MLB |
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| 12 | 4 | 92 | 2001 | Inaugural Draft | 2B | Mark | Grudzielanek | MLB |
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| 1 | 2 | 2 | 2000 | Annual Draft | OF | Albert | Belle | MLB |
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| 2 | 8 | 16 | 2000 | Annual Draft | P | Rick | Ankiel | MLB |
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| 3 | 2 | 18 | 2000 | Annual Draft | P | Kris | Benson | MLB |
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| 4 | 2 | 26 | 2000 | Annual Draft | P | Gabe | White | MLB |
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| 5 | 2 | 34 | 2000 | Annual Draft | P | John | Wetteland | MLB |
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| 6 | 2 | 42 | 2000 | Annual Draft | OF | Doug | Glanville | MLB |
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| 7 | 2 | 50 | 2000 | Annual Draft | P | Todd | Jones | MLB |
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| 8 | 2 | 58 | 2000 | Annual Draft | P | Todd | Ritchie | MLB |
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